Table 1.
Patient characteristics at diagnosis
| Number (%) | |
|---|---|
| n | 21 |
| Sex | |
| Male | 8 (38) |
| Female | 13 (62) |
| Age at diagnosis (years) | |
| Median (range) | 1.6 (0–5.5) |
| ≤1 year | 9 (43) |
| INSS stage | |
| 1 | 4 (19) |
| 2 | 3 (14) |
| 3 | 14 (67) |
| Histology | |
| Neuroblastoma | 17 (81) |
| Ganglioneuroblastoma | 4 (19) |
| Localisation | |
| Neck | 1 (5) |
| Thoracic | 5 (24) |
| Abdominal | 11 (52) |
| Pelvic | 4 (19) |
| Intraspinal component | 7 (33) |
| Genetic aberrations | |
| MNA | 2/18 |
| 1pLOH | 1/18 |
| Both | 1/18 |
| Urinary catecholamines | |
| Elevated | 18/21 |
| Normal | 3/21 |
| LDH | |
| 0–1 year (≥400 U/l) | 3/9 |
| 1–17 years (≥300 U/l) | 3/12 |
| Ferritin | |
| ≥143 ng/ml | 4/18 |
n number of patients, INSS International Neuroblastoma Staging System, MNA MYCN amplification, 1pLOH chromosome 1p loss of heterozygosity, LDH lactate dehydrogenase