Table 4.
Significant metabolism/antioxidant gene SNP – fruit, vegetable, fiber, and grain intake category interactions that are associated with pancreatic adenocarcinoma. Interactions in this table are determined significant based on the interaction and permutation test Ps ≤ 0.0007.
Minor Allele Frequency (Control %/Case %) | Odds Ratio (95% CI) | P | |||||||
---|---|---|---|---|---|---|---|---|---|
|
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Gene | Influence | number | Nutrient | 0 | ≥ 1 | 0 | ≥ 1 | tion | tion |
CAT | 5′upstream | rs12807961 | Low total grains | 20.18/12.35 | 29.77/35.46 | 1.00 (ref) | 2.05 (1.28,3.28) | 0.0007 | 0.0003 |
High total grains | 20.07/24.70 | 29.99/27.49 | 2.48 (1.50,4.09) | 1.74 (1.07,2.83) | |||||
GAA | 5′upstream | rs3816257 | Low deep-yellow vegetables | 20.95/18.40 | 29.22/48.40 | 1.00 (ref) | 1.90 (1.28,2.83) | 0.0004 | 0.0005 |
High deep-yellow vegetables | 17.20/15.20 | 32.64/18.00 | 1.07 (0.65,1.76) | 0.66 (0.42,1.05) |