Fig. 3.
Cytochalasin-D inhibits LDL uptake through a scavenger receptor-independent mechanism. The relative CD36 and SR-A mRNA expression was determined in THP-1 macrophages incubated with Cytochalasin-D (2.5 μg/ml, n = 3). Gene-specific mRNA expression levels were calculated using the comparative Ct method and normalized to RPL13A levels with vehicle treated cells given an arbitrary value of 1. DMSO was used as a vehicle control. Data represents the mean ± SD. Statistical analysis was performed using the Student’s t-test, *P < 0.05.