Table 3.

Follow up details

	Overall (N=14)	Dose Level 1 (N=8)	Dose Level 2 (N=6)
Number cycles received, median(range)	2 (1,5)	2 (2,5)	3 (1,4)
Follow-up Status
Alive	9 (64.3%)	5 (62.5%)	4 (66.7%)
Dead	5 (35.7%)	3 (37.5%)	2 (33.3%)
Progression Status
Yes	10 (71.4%)	7 (87.5%)	3 (50%)
No	4 (28.6%)	1 (12.5%)	3 (50%)
Off Active Treatment
Yes	14 (100%)	8 (100%)	6 (100%)
Reason End Treatment
Progression Onstudy	10 (71.4%)	7 (87.5%)	3 (50%)
Refused Further Rx	1 (7.1%)	1 (12.5%)	0 (0%)
AEs/Side Effects	3 (21.4%)	0 (0%)	3 (50%)