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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Neurobiol Aging. 2013 Jul 21;34(12):2748–2758. doi: 10.1016/j.neurobiolaging.2013.06.007

Figure 7. The aged-associated increase in brain levels of miR-29a and miR-29b was negatively correlated with reduced expression of CX3CL1 and IGF-1.

Figure 7

Postmortem brain tissue was acquired for both adult (n=9) and aged (n=13) age groups. From the human brain tissue mRNA expression of A) IL-1β, B) IGF-1, and C) CX3CL1 was determined. In addition, a correlation plot was created for IGF-1 and CX3CL1 compared to miR-29a or miR-29b levels determined in Fig.5. Plots depict expression levels of miR-29a versus D) IGF-1 and E) CX3CL1 in the human brain tissue. In addition, levels of miR-29b versus F) IGF-1 and G) CX3CL1 are shown. Bars represent the mean ± SEM. Relative expression is compared to the average comparative Ct for all samples. Means with * are significantly (p<0.04) different from Adult controls.