A detailed difference of the expression rates of MUC4/8G7 (A) and MUC4/1G8 (B) in each dysplastic lesions between the 221 lesions of gastric-type IPMN and the 118 lesions of intestinal-type IPMN. The positive expression rates of MUC4/8G7 in the intestinal-type IPMNs were significantly higher than those in the gastric-type IPMNs (A). The positive expression rates of MUC4/1G8 in the intestinal-type IPMNs were significantly higher than those in the gastric-type IPMNs (B). In the gastric-type IPMNs, both MUC4/8G7 and MUC4/1G8 expression rates increased significantly with increasing the dysplastic grades (A and B). In each histological dysplastic grade, the positive expression rate of MUC4/8G7 in the intestinal-type IPMN-L was significantly lower than that of MUC4/1G8 in the intestinal-type IPMN-L (P<0.05) (A and B, arrows). L indicates low-grade dysplasia; I, intermediate-grade dysplasia; H, high-grade dysplasia including carcinoma in situ; IC, invasive carcinoma; ★★★, P<0.001; ★★, P<0.01; ★, P<0.05.