Table 2.
Selected list of genes with lower expression in Kashin-Beck disease (KBD) than osteoarthritis (OA)
| Function | Public ID | Gene symbol | Differential fold change, mean ± SEM |
|---|---|---|---|
| Macrophage related | NM_004864 | GDF15 | 0.23 ± 0.12 |
| Aggrecan Metabolism | |||
| Miscellaneous | AK098514 | CSGALNACT | 0.04 ± 0.007 |
| Metabolism | NM_003033 | ST3GAL1 | 0.04 ± 0.008 |
| Glucose metabolism | NM_005566 | LDHA | 0.32 ± 0.23 |
| Oncogene related | NM_001015049 | BAG5 | 0.26 ± 0.2 |
| DNA modification | NM_018371 | ChGn | 0.4 ± 0.22 |
| Cytokine | NM_003278 | CLEC3B | 0.33 ± 0.12 |
| Cytokine/growth factor | NM_000201 | ICAM1 | 0.34 ± 0.29 |
| Lysosome related | NM_005561 | LAMP1 | 0.015 ± 0.001 |
| Extracellular matrix relate | NM_001884 | HAPLN1 | 0.44 ± 0.13 |