Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Feb 18;68(10):1135–1144. doi: 10.1093/gerona/glt016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PMC Copyright notice

Figure 4. — SKN-1 and the hypoxic response. This figure shows life spans of Caenorhabditis elegans cultured at 20°C on UV-killed OP50 bacteria in both normoxia (21% O₂) and hypoxia (0.5% O₂) throughout adulthood. (A) In hypoxic conditions, skn-1(zu-67) mutants increase median life span 14.3% and (B) skn-1(zu135) mutant worms increase median life span by 22.2% (p values 9.0E-13 and 5.8E-16, respectively). (C) ls007 (skn-1b/c::gfp) worms (overexpressing SKN-1) have a median life-span decrease of −21.7% (p value 8.0E-6). Composite of all trials are shown. Significance: **p < .001.