Table 3. Mortality From Cancer or Other Causes at 1 and 5 Years After a Diagnosis of Breast, Colon, or Prostate Cancer.
Cancer-Specific Mortality,a % | Noncancer Mortality,a % | |||||||
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1y | 5y | 1y | 5y | |||||
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Cancer and Dementia Status | Mortality | Excess Dementia Mortality (95% CI) | Mortality | Excess Dementia Mortality (95% CI) | Mortality | Excess Dementia Mortality (95% CI) | Mortality | Excess Dementia Mortality (95% CI) |
Breast | ||||||||
Dementia | 7.6 | 3.8 (2.7 to 4.7) | 17.9 | 4.8 (1.4 to 8.4) | 9.0 | 6.0 (4.8 to 7.3) | 31.8 | 15.6 (11.2 to 20.2) |
No dementia | 3.8 | 13.1 | 3.0 | 16.2 | ||||
Colon | ||||||||
Dementia | 25.5 | 7.9 (5.8 to 10.1) | 37.1 | 3.5 (−0.9 to 8.1) | 16.8 | 7.7 (6.0 to 9.5) | 36.4 | 12.8 (8.4 to 17.4) |
No dementia | 17.6 | 33.6 | 9.1 | 23.6 | ||||
Prostate | ||||||||
Dementia | 2.1 | 0.8 (0.3 to 1.3) | 11.7 | 2.8 (0.4 to 5.5) | 4.2 | 1.7 (1.0 to 2.5) | 33.2 | 12.7 (8.4 to 17.2) |
No dementia | 1.3 | 8.9 | 2.5 | 20.5 |
Abbreviation: CI, confidence interval.
The cancer and noncancer excess mortality associated with a dementia diagnosis was estimated from logistic regression models adjusted for age, comorbidities (other than dementia), and other demographic factors. The regression analyses assessed deaths from cancer and deaths from all other causes separately. For the 5-year excess mortality, only patients diagnosed from January 1994 through December 1996 with 5 years of follow-up were included (n=16 173, 13 766, and 24 693 for patients with breast, colon, and prostate cancer, respectively). For each of the three cancers, dementia was associated with a greater absolute increase in deaths from noncancer causes than deaths from cancer causes.