Table 1.
Mean duration (s) of social states for MAC IgG and control monkeys across social testing paradigms
| Behavioral State | Prewean Mother–infant dyads
|
Prewean social groups
|
Postwean familiar dyads
|
Postwean unfamiliar dyads
|
Postwean social groups
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAC IgG
|
Control
|
MAC IgG
|
Control
|
MAC IgG
|
Control
|
MAC IgG
|
Control
|
MAC IgG
|
Control
|
|||||||||||
| Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | |
| Breast contact | 619.53 | 217.13 | 312.04 | 73.02 | 682.95 | 258.57 | 446.94 | 183.37 | * | * | * | * | * | * | * | * | * | * | * | * |
| Ventral contact | 1109.88 | 318.96 | 1293.52 | 147.08 | 327.65 | 286.77 | 461.24 | 194.48 | * | * | * | * | * | * | * | * | * | * | * | * |
| Other contact | 1482.92 | 148.02 | 1170.40 | 106.93 | 1585.67 | 124.37 | 1162.91 | 102.18 | * | * | * | * | * | * | * | * | * | * | * | * |
| Extended play | 26.25 | 11.59 | 103.89 | 29.06 | 167.26 | 82.73 | 365.39 | 94.59 | 3.73 | 3.73 | 11.00 | 3.75 | 44.42 | 32.65 | 33.54 | 14.64 | 161.87 | 30.62 | 339.01 | 74.71 |
| Nonsocial active | 1451.23 | 402.39 | 1932.41 | 232.81 | 1687.75 | 476.09 | 2592.41 | 284.81 | 4235.61 | 186.10 | 3430.68 | 239.00 | 4055.24 | 139.54 | 4088.95 | 116.86 | 4357.64 | 90.52 | 3658.96 | 195.98 |
| Proximity | 1272.67 | 176.71 | 1142.05 | 67.08 | 1276.85 | 381.07 | 1495.93 | 115.51 | 832.30 | 180.92 | 1078.92 | 82.42 | 313.65 | 68.61 | 369.08 | 67.47 | 821.30 | 83.69 | 983.78 | 55.49 |
| Extended groom | * | * | * | * | 0.00 | 0.00 | 4.53 | 2.62 | 36.93 | 36.93 | 46.30 | 26.00 | 6.44 | 4.84 | 67.66 | 36.54 | 173.39 | 49.31 | 294.28 | 85.06 |
| Extended toy play | ** | ** | ** | ** | 15.70 | 6.41 | 11.91 | 3.51 | 7.12 | 0.36 | 77.62 | 24.11 | 3.76 | 3.76 | 19.84 | 7.57 | 105.69 | 49.23 | 158.89 | 39.37 |
| Extended contact | * | * | * | * | * | * | * | * | 353.19 | 125.09 | 811.80 | 113.14 | 161.29 | 39.05 | 135.42 | 35.98 | 1018.86 | 105.89 | 1071.86 | 122.10 |
| Sleep | * | * | * | * | * | * | * | * | 22.28 | 20.61 | 23.34 | 9.91 | ** | ** | ** | ** | 470.60 | 163.41 | 551.42 | 86.97 |
There were no differences in important maternal–infant interactions such as ventral–ventral contact. During the preweaning social groups, MAC IgG treated infants spent significantly more time in contact with their mother and peers than control infants (t(11) = 2.410, p = .035). During the postweaning familiar dyads, MAC IgG treated monkeys spent significantly less time in the extended contact state with their peers (t(11) = 2.403, p = .035) and showed a trend towards more time in a nonsocial active state than control monkeys (t(11) = 2.088, p = .061). The increase in nonsocial active behavior was also observed in postweaning social groups (t(11) = 2.279, p = .044).
Indicates that the social state was not applicable to the testing paradigm.
Indicates insufficient data due to the rare occurrence of the social state within the testing paradigm. Bold font indicates significant differences between control and MAC IgG monkeys.