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. Author manuscript; available in PMC: 2014 Jun 25.
Published in final edited form as: Biochemistry. 2013 Jun 11;52(25):4391–4398. doi: 10.1021/bi400264d

Figure 2.

Figure 2

A generalized view of the proposed mechanism of UGM, depicting a covalent flavin intermediate. The arrows shown depict changes in covalent bond formation, but whether the mechanism proceeds via an SN1 or SN2 reaction is not known nor is the protonation state of the flavin cofactor. A key intermediate in this proposal is iminium ion 1.