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Cpr6 function requires sequences flanking the TPR domain. A and B, strains JJ816 (hsc82hsp82) and JJ110 (cpr6hsc82hsp82) expressed hsp90-A587T. Cells were transformed with pRS416 or a plasmid expressing WT or mutant Cpr6. Growth of 10-fold serial dilutions on selective media was monitored after 2 days at the indicated temperatures.
