TLQP-21-induced calcium fluxes measured in several cell lines.
A, calcium measurements of rat (● and ○) and human (■ and □) TLQP-21 without (● and ■) or with (○ and □) PTX in CHO-K1 cells after ATP priming. B, calcium measurements of positive control (▴; ATP, bradykinin, carbachol, sphingosine 1-phosphate, and lysophosphatidic acid 18:0) and rat (●) TLQP-21-triggered responses after ATP priming in CCL39 cells. C, calcium measurements of rat TLQP-21-triggered responses after ATP priming in O-342 cells. All data are represented as signal − base line/base-line signal (ΔF/F) ± S.D.