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. Author manuscript; available in PMC: 2013 Sep 23.
Published in final edited form as: J Inherit Metab Dis. 2010 May 11;33(3):261–270. doi: 10.1007/s10545-010-9109-3

Fig. 3.

Fig. 3

BCR receptor and co-receptors are downregulated in Hexb−/− (Sandhoff disease) B cells. Spleens of 14-week-old mice were taken to determine the level of expression of CD21, CD19, CD40, MHC II, and sIgM on CD23 high B cells by FACS. A 2-way ANOVA analysis was performed and raft and non-raft components where significantly different, p<0.05). The level of expression of sIgG in control and Sandhoff human lymphoblasts were also determined by FACS. Solid bars represent Sandhoff B cells. *p<0.05