A. Concentrations of blood KS in MPS IVA patients and normal individuals. Blood samples taken from 38 MPS IVA subjects (mean age, 9.8 years; range, 0.5–46.9 years) and 234 control subjects (mean age, 18.6 years; 0–50 years). KS levels ranged between 97 ng/ml and 1,192 ng/ml (mean, 526 ± 263 ng/ml) for MPS IVA patients and 3 and 323 ng/ml (122 ± 73 ng/ml) for control subjects.
B. Concentrations of urine KS in MPS IVA patients and normal individuals. Urine KS results taken from 33 MPS IVA subjects (mean age, 8.6 years; 0.5– 24 years) and 178 control subjects (mean, 9.7 years; range, 0–50 years).
C. Concentrations of urine GAGs in MPS IVA patients and normal individuals. Urine GAG results taken from 36 MPS IVA subjects (mean, 8.8 years; 0.5–24 years) and 165 control subjects (mean, 9.9 years; range, 0–50 years).