Table 4.
KS levels in MPS IVA patients with attenuated and severe phenotypes
| Attenuated | Urine KS (mg/gCre) | Blood KS (ng/ml) | Severe | Urine KS (mg/gCre) | Blood KS (ng/ml) | |
|---|---|---|---|---|---|---|
| Over 5 years* | Mean | 2.4 | 410.4 | Mean | 6.7 | 564.4 |
| SD | 4.3 | 196.9 | SD | 6.4 | 359.4 | |
| n | 21 | 24 | n | 43 | 43 | |
|
| ||||||
| Under 5 years# | Mean | Mean | 11.0 | 573.9 | ||
| SD | SD | 12.7 | 224.1 | |||
| n | n | 20 | 23 | |||
|
| ||||||
| 5 to 15 years** | Mean | 3.5 | 486.4 | Mean | 8.6 | 689.5 |
| SD | 5.5 | 204.7 | SD | 7.1 | 349.1 | |
| n | 12 | 14 | n | 28 | 29 | |
|
| ||||||
| Over 15 years*** | Mean | 1.0 | 392.4 | Mean | 3.0 | 305.3 |
| SD | 1.0 | 361.7 | SD | 2.1 | 217.9 | |
| n | 9 | 10 | n | 15 | 14 | |
*
Urine KS, P = 0.0029; blood KS, P = 0.0385
**
Urine KS, P = 0.0199; blood KS, P = 0.0196
***
Urine KS, P = 0.6647; P = 0.7614
#
Data for urine KS is not available in the patients with an attenuated phenotype.