Table 3. Correlation ρC of the cluster fluctuations for the first (M1), the second (M2) and the third (M3) disjoint sets of the 24 human chromosome sequences. The fluctuations are anticorrelated with length, gene density, inter-chromosomal and intra-chromosomal segmental duplications, while they exhibit a positive correlation with the AT-rich regions. Very little correlation is found with the GC-rich regions and global AT composition. Length values are shown in the 2nd column of Table 1. Gene density data are taken from Refs. 14, 15. Inter- and intra-chromosomal duplications data are taken from Ref. 14. Base compositions are shown in Table 1 (respectively 4th–7th columns for the whole sequence, 8th–11th columns for the first 10MBases, and in Tables S1–S6 of the Supplementary Information).
ρC [M1] | ρC [M2] | ρC [M3] | |
---|---|---|---|
Length | −0.194 | −0.552 | −0.582 |
Gene density | −0.178 | −0.076 | −0.107 |
Inter-chromosomal duplications | −0.330 | −0.242 | −0.165 |
Intra-chromosomal duplications | −0.342 | −0.248 | −0.158 |
All pairwise duplications | −0.331 | −0.237 | −0.149 |
Local composition A | +0.658 | +0.762 | +0.461 |
Local composition T | +0.668 | +0.674 | +0.551 |
Local composition C | +0.021 | +0.039 | +0.269 |
Local composition G | −0.149 | +0.211 | +0.246 |
Global composition AT | +0.052 | −0.154 | −0.219 |