Table 2.
Tests of Hardy–Weinberg equilibrium and frequencies by allele and genotype for the participants of European ancestry.
| Gene/SNP | Frequency |
Hardy–Weinberg equilibrium |
|||
|---|---|---|---|---|---|
| Allele/genotype | n | % | χ2 | df | p Value |
| ANKK1 rs1800497 | 0.00 | 1 | 1.00 | ||
| T | 48 | 25.0 | |||
| C | 144 | 75.0 | |||
| T/T | 6 | 6.3 | |||
| T/C | 36 | 37.5 | |||
| C/C | 54 | 56.3 | |||
| DRD2 rs1079597 | 8.46 | 1 | 0.004 | ||
| A | 59 | 30.7 | |||
| G | 133 | 69.3 | |||
| A/A | 3 | 3.1 | |||
| A/G | 53 | 55.2 | |||
| G/G | 40 | 41.7 | |||
| DRD2 rs1799732 | 5.46 | 1 | 0.05 | ||
| Ins | 171 | 90.0 | |||
| Del | 19 | 10.0 | |||
| Ins/Ins | 79 | 83.2 | |||
| Ins/Del | 13 | 13.7 | |||
| Del/Del | 3 | 3.2 | |||
| CHRNA5 rs16969968 | 1.17 | 1 | 0.39 | ||
| A | 71 | 35.2 | |||
| G | 131 | 64.8 | |||
| A/A | 10 | 9.9 | |||
| A/G | 51 | 50.5 | |||
| G/G | 40 | 39.6 | |||
| CHRNA3 rs1051730 | 0.57 | 1 | 0.52 | ||
| A | 71 | 35.9 | |||
| G | 127 | 64.1 | |||
| A/A | 11 | 11.1 | |||
| A/G | 49 | 49.5 | |||
| G/G | 39 | 39.4 | |||
| CHRNA3 rs578776 | 1.23 | 1 | 0.26 | ||
| T | 45 | 22.5 | |||
| C | 155 | 77.5 | |||
| T/T | 7 | 7.0 | |||
| C/T | 31 | 31.0 | |||
| C/C | 62 | 62.0 | |||
| CHRNB2 rs2072661 | 0.87 | 1 | 0.43 | ||
| A | 50 | 25.0 | |||
| G | 150 | 75.0 | |||
| A/A | 8 | 8.0 | |||
| A/G | 34 | 34.0 | |||
| G/G | 58 | 58.0 | |||
| LOC123688 rs8034191 | 0.98 | 1 | 0.40 | ||
| C | 70 | 35 | |||
| T | 130 | 65 | |||
| C/C | 10 | 10 | |||
| C/T | 50 | 50 | |||
| T/T | 40 | 40 | |||