Figure 6.
Correlations between circulating glucocorticoids and hippocampal and cortical expression of Aβ and ptau. Cortical expression of both Aβ and ptau are positively, significantly (p<0.028) correlated with circulating glucocorticoids measured 1 week after the start of the sleep restriction period (A–B). In the hippocampus, Aβ, but not ptau, is significantly correlated with circulating glucocorticoids (p=0.032; C–D). Circulating corticosterone was negatively and significantly (p=0.045) correlated with the percent time spent in the target quadrant during the 24 hour probe test (E).