Table 1.
Baseline Characteristics of Atorvastatin-Treated Subjects Who Did or Did Not Double Their Baseline Creatine Kinase Value
| CK < 2x baseline (n = 178) | CK > 2x baseline (n = 24) | P | |
|---|---|---|---|
| Male, n (%) | 88 (49.4) | 12 (50.0) | 0.96 |
| Age, yrs | 43.4 ± 16.4 | 43.3 ± 12.1 | 0.97 |
| Height, cm | 170.9 ± 9.5 | 171.8 ± 8.9 | 0.67 |
| Weight, kg | 77.4 ± 17.1 | 79.1 ± 17.8 | 0.65 |
| BMI, kg/m2 | 26.2 ± 4.7 | 26.8 ± 5.3 | 0.61 |
| Waist, cm | 85.1 ± 13.7 | 87.8 ± 14.6 | 0.40 |
| Resting HR, bpm | 68 ± 11 | 71 ± 13 | 0.24 |
| Resting SBP, mmHg | 119 ± 13 | 122 ± 13 | 0.30 |
| Resting DBP, mmHg | 76 ± 10 | 74 ± 8 | 0.48 |
| Total-C, mg/dL | 198.8 ± 38.3 | 196.8 ± 47.6 | 0.82 |
| HDL-C, mg/dL | 57.7 ± 17.2 | 57.1 ± 17.0 | 0.88 |
| LDL-C, mg/dL | 119.3 ± 34.4 | 116.5 ± 44.1 | 0.72 |
| TG, mg/dL | 109.4 ± 54.3 | 118.3 ± 64.7 | 0.46 |
| CK, U/L | 138.7 ± 126.5 | 85.0 ± 44.6 | 0.01 |
Data are means ± SD. BMI = body mass index; C = cholesterol; CK = creatine kinase; DBP = diastolic blood pressure; HDL-C = high-density lipoprotein; HR = heart rate; LDL = low-density lipoprotein; SBP = systolic blood pressure; TG = triglycerides.