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Putamen ceruloplasmin as a function of (a) spontaneous baseline activity (before initiation of the treadmill running study) or (b) overall activity during the study (includes spontaneous daily activity and treadmill running activity) in intact, healthy monkeys. c, d, e, and f: Correlations between spontaneous or overall activity and tyrosine hydroxylase (TH) in indicated brain regions of MPTP-treated monkeys. The right hemisphere was infused with MPTP.
