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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: Angew Chem Int Ed Engl. 2013 Feb 28;52(14):3931–3934. doi: 10.1002/anie.201209303

Figure 4. Subcellular Abl inhibition by imatinib.

Figure 4

MEFs were treated with the biosensor and imaged before (t = 0) or after (t = 5, 8 min) adding the Abl inhibitor imatinib. Arrow shows selected control cell (top panels). B) Plot of lifetime distribution for cells shown as well as longer timepoints (0–20 min). Additional timepoint images, and plots for several subcellular ROIs for multiple cells, are shown in the supporting information.