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Cardiac fibroblast proliferation (A), cardiac fibroblast hydroxyproline (HPro) release (B), and matrix metalloproteinase-2 (MMP-2) activity (C) in medium in response to coculture of cardiac fibroblasts with untreated inflammatory cells (IC) and cardiac inflammatory cells in conjunction with a neutralizing antibody against TNF-α (IC + anti-TNF-α). *P < 0.05 versus control; #P < 0.05 versus IC.
Abbreviations: BrdU, 5-bromo-2′-deoxyuridine; TNF-α, tumor necrosis factor-alpha.
