Table 1.

Characteristics of the Six Genetic Variants Associated with Hypertension

Gene	SNP	Year	Author	Ethnic group	Genotype (case/control)			Allele (case/control)
HSD3B1	T→C Leu338				TT	TC	CC	T	C
		2002	Rosmond et al.	Swedish	4/26	20/68	15/21	28/120	50/110
		2004	Speirs et al.	Australian	20/60	71/109	32/61	111/229	135/231
		2010	Shimodaira et al.	Japanese	122/129	114/133	39/24	358/391	192/181
HTR2A	T102C				CC	CT	TT	C	T
		2001	Liolitsa et al.	British	124/87	172/174	46/58	420/348	264/290
		2004	Yu et al.	Chinese	34/31	68/67	96/66	136/129	260/199
		2006	Yamamoto et al.	Japanese	298/467	517/899	287/500	1113/1833	1091/1899
GNAS	T393C				TT	TC	CC	T	C
		2002	Abe et al.	Japanese	297/532	486/904	184/404	1080/1968	854/1712
		2003	Chen et al.	Japanese	238/500	342/776	119/333	818/1776	580/1442
		2004	Yamamoto et al.	Japanese	87/187	126/254	54/113	300/628	234/480
CYP4A11	T8590C				TT	CT	CC	T	C
		2005	Gainer et al.	American	126/152	64/41	5/4	316/345	74/49
		2005	Mayer et al.	German	481/574	149/164	19/10	1111/1312	187/184
		2006	Mayer et al.	German	152/250	68/79	8/3	372/579	84/85
		2008	Fu et al.	Japanese	179/133	122/64	3/10	480/330	128/84
		2008	Sugimoto et al.	Japanese	325/326	157/153	13/15	807/805	183/183
RGS2	1891-1892del TC				II	ID	DD	I	D
		2005	Yang et al.	Japanese	257/420	391/513	123/169	905/1353	637/851
		2008	Zhao et al.	Chinese	690/758	1229/1168	474/411	2609/2684	2177/1990
		2010	Li et al.	Xinjiang Kazak	177/227	214/215	53/47	568/669	320/309
		2011	Kamide et al.	Japanese	300/646	410/862	124/272	1010/2154	658/1404
RGS2	G638A				GG	GA	AA	G	A
		2005	Yang et al.	Japanese	174/220	389/554	208/328	737/994	805/1210
		2008	Kohara et al.	Japanese	603/663	1520/1837	1104/1224	2726/3163	3728/4285
		2009	Ruixing et al.	Chinese	46/165	118/446	93/254	210/776	304/954
		2011	Kamide et al.	Japanese	174/369	413/890	243/519	761/1628	899/1928

SNP, single-nucleotide polymorphism.