Table 4.

CB1 receptor agonists and properties of psychostimulants.

Agonists	Drugs	Models	Outcome	Effects	Reference
CP55,940	Cocaine	Mouse	SA – effect of agonist after drug-taking extinction	No effect	Vaughn et al. (276)
		Rat	SA – behavior acquisition following exposure during adolescence in female specimen	Enhanced	Higuera-Matas et al. (291)
	MDMA	Rat	SA – drug-seeking responses/intake	Decreased	Braida and Sala (288)
HU210	Cocaine	Rat	SA – effect of agonist after drug-taking extinction	Reinstatement	De Vries et al. (283)
Δ9-THC	Amphet.	Rat	CPP – behavior acquisition	Preserved	Parker et al. (290)
			CPP – behavior extinction	Potentiated	Parker et al. (290)
	Cocaine	Monkey	SA – effect of agonist after drug-taking extinction	Reinstatement	Justinova et al. (260)
		Mouse	Drug-induced motor sensitization	Preserved	Gerdeman et al. (268)
		Rat	Drug-induced acute hyperlocomotion	Preserved	Panlilio et al. (272)
			Drug-induced motor sensitization	Preserved	Panlilio et al. (272)
			Drug-induced anxiety	Increased	Panlilio et al. (272)
			SA – behavior acquisition	Preserved	Panlilio et al. (272)
			SA – drug-seeking responses under PR schedule	Decreased	Panlilio et al. (272)
			CPP – behavior extinction	Potentiated	Parker et al. (290)
	METH	Rat	SA – cue-induced reinstatement	Increased	Anggadiredja et al. (289)
			SA – drug-induced reinstatement	Attenuated	Anggadiredja et al. (289)
WIN-55	Cocaine	Rat	Drug-induced acute hyperlocomotion	Attenuated	Przegalinski et al. (270), Vlachou et al. (252)
			Drug-induced lowering of brain reward/self-stimulation threshold	Impaired	Vlachou et al. (251)
			SA – drug-seeking responses/intake	Decreased	De Vries et al. (283)
	MDMA	Mouse	CPP – behavior acquisition	Increased	Rodriguez-Arias et al. (286)
			CPP – time for behavior extinction	Increased	Rodriguez-Arias et al. (286)
			CPP – drug-induced reinstatement	Increased	Rodriguez-Arias et al. (286), Daza-Losada et al. (285)