Table 1.

Quantitative Histopathology

Lesion	VC	APRV
% Air Space	40.8 ± 5.7	72.0 ± 6.4*
Fibrinous Deposits	1.82 ± 0.15	0.00 ± 0.17*
Hemorrhage in air space	0.22 ± 0.09	0.65 ± 0.10*
Capillary congestion	0.92 ± 0.16	0.58 ± 0.18
Thickened alveolar walls	2.00 ± 0.14	0.85 ± 0.15*
Cellular infiltration	1.98 ± 0.11	0.35 ± 0.12*

Volume Cycled ventilation (VC) and Airway Pressure Release Ventilation (APRV) groups. % Air Space is the percent of the microscopic field occupied by inflated alveoli measured with the in vivo microscope at peak inspiration. All other lesions were measured on histologic sections. See Methods for description of Lesions and for scoring method. Histologic lesions score range = 0 to 4; Number of microscopic fields examined: VC n=50 and APRV n=40. % Air Space measured as the percent of inflated alveoli/microscopic filed; Number of microscopic fields examined: VC n=5 and APRV n=4. Data are Mean ± SEM.

^*p<0.05