Table 2.

Risk Factors for VTE in Patients With Cancer

Category	Risk Factor
Patient characteristics	Advanced age Gender Ethnicity ○ African American, higher ○ Asian, lower
Cancer-related factors	Cancer site ○ Brain ○ Pancreas ○ Kidney ○ Stomach ○ Bladder ○ Gynecologic ○ Lung ○ Blood Advanced stage Initial post-diagnosis
Biomarkers	Increased platelet count prior to chemotherapy D-dimer Tissue factor expression in tumor cells
Treatment-related factors	Major surgery Hospitalization Cancer therapy Chemotherapy or hormonal therapy Antiangiogenic and immunomodulatory agents ○ Bevacizumab ○ Thalidomide and lenalidomide Erythropoiesis-stimulating agents

Reprinted from Thrombosis Research, Vol 120 Supplement 2, Alok A. Khorana, Maithili V. Rao, Approaches to risk-stratifying cancer patients for venous thromboembolism, Pages No. S41-S50, Copyright 2007, with permission from Elsevier.¹⁴