Table 2.
Staging and grading of acute graft-versus-host [12]
| Stage | Skin | Liver | Gut |
|---|---|---|---|
| 1 | Rash <25% of body surface area | Bilirubin 2–3 mg/dl | Diarrhoea 500–1000 ml/day or persistent nausea |
| 2 | Rash 25–50% of body surface area | Bilirubin 3–6 mg/dl | Diarrhoea 1000–1500 ml/day |
| 3 | Rash >50% of body surface area | Bilirubin 6–15 mg/dl | Diarrhoea >1500 ml/day |
| 4 | Erythroderma with bullae formation | Bilirubin >15 mg/dl | Severe abdominal pain with or without ileus |
| Grade | |||
| I | Stage 1–2 | None | None |
| II | Stage 3 or | Stage 1 or | Stage 1 |
| III | Stage 2–3 or | Stage 2–4 | |
| IV | Stage 4 or | Stage 4 | |