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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Exp Cell Res. 2013 Jun 7;319(16):2434–2439. doi: 10.1016/j.yexcr.2013.05.030

Figure 1. Fibroblast migration in 3D cell-derived matrix.

Figure 1

Left: Maximum projection confocal image of a human foreskin fibroblast (HFF) embedded within a matrix containing oriented CDM fibronectin fibrils (magenta, anti-fibronectin immunostaining). Cytoskeletal architecture visualized by staining for actin (blue, phalloidin) and paxillin-containing focal adhesions (yellow, anti-paxillin). Right: Maximum projection image of focal adhesion profile of paxillin-containing adhesions during migration in CDM.