TABLE V.
Predicted transcription factor binding sites within the protected sequences.
| 5′ | 3′ | Number of Predicted Transcription Factor Binding Sites within the Protected Sequence | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AP-4 | AREB6 | ARP-1 | CREB | c-Rel | E47 | Elk-1 | HLF | NF-E2 | B (p50) κ NF- | 1 α ROR | RREB-1 | ZID | |||
| Location of Protected Sites Relative to the TSS | −354 | −302 | - | 1 | 1 | 3 | 9 | - | - | 1 | 1 | - | 1 | - | - |
| −284 | −264 | - | - | - | - | 2 | - | - | - | - | - | - | - | - | |
| −254 | −236 | - | - | - | 1 | 3 | - | - | - | 1 | - | - | - | 1 | |
| −231 | −224 | - | - | - | - | 1 | - | - | - | - | - | - | - | - | |
| −212 | −205 | - | - | - | - | 1 | - | - | - | - | - | - | - | - | |
| −85 | −69 | - | - | - | - | - | - | - | - | - | - | - | 1 | - | |
| −26 | −3 | - | - | - | - | 6 | - | 1 | - | - | - | - | - | - | |
| +10 | +20 | 1 | - | - | 1 | 1 | - | - | - | - | - | - | - | - | |
| +26 | +32 | - | - | - | - | - | - | - | - | - | - | - | - | - | |
The chart depicts the number of transcription factor binding sites that overlap at all with the DNase protected sequences summarized in Table IV. The sites were identified with P-Match (gene-regulation.org) using an algorithm that filters for vertebrate transcription factors and minimizes false negatives. Only the human transcription factor binding sites are shown below.