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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Dec 27;268(3):249–255. doi: 10.1016/j.taap.2012.12.009

Figure 2.

Figure 2

NO-sulindac reduces the expression of pro-inflammatory MAP kinases, alters tyrnitrosylation and reduces the expression of epithelial-mesenchymal transition regulating proteins. (A) Immunofluroscence staining of paraffin-fixed tumor tissues showing the expression of p-lκBα (Ser32/36), iNOS & COX-2: (B) expression of p-Erk1/2, p-38 & p-JNK1/2; (C) tyrnitrosylation in murine SCCs & in A431 cells; (D) immunofluorescence staining/western Wot analysis showing the expression of E-cadherin, Fibronection, N-cadherin, Twist, SNAI & Slug.