Table 1.
Clinical characteristics of PD patients
| N | Age | Handedness | Time post surgery (years) |
Disease durationa (years) |
UPDRSb (ON-DBS) |
H & Yc stage (ON-DBS) |
UPDRS (OFF-DBS) |
H & Y stage (OFF-DBS) |
Medications |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 77 | R | 1.5 | 6 | 39 | 3 | 45 | 3.0 | Lev, Sel, Rop, Am |
| 2 | 72 | R | 2.7 | 11 | 40 | 3 | 49 | 3 | St, Rop, Par |
| 3 | 79 | R | 4 | 8 | 28 | 2 | 44 | 2 | Lev; St |
| 4d | 76 | R | 0.8 | 13 | 37 | 3 | 52 | 3 | None |
| 5 | 68 | R | 3 | 16 | 31 | 2 | 42 | 2 | Lev; Pr; Ent |
| 6 | 60 | R | 4 | 15 | 44 | 2 | 63 | 3 | Lev; LevR; Rop;Ent |
| 7 | 68 | R | 2 | 14 | 34 | 3 | 42 | 3 | Lev; St; RopXL; Ras |
| 8 | 60 | R | 1 | 10 | 41 | 3 | 48 | 3 | Lev; Pr; Ras |
| 9 | 61 | R | 1 | 10 | 28 | 3 | 39 | 3 | St; Pr |
| 10 | 76 | R | 3.7 | 10 | 37 | 3 | 51 | 3 | Lev; Ras |
| 11 | 61 | R | 3 | 7 | 32 | 3 | 50 | 3 | Lev |
| 12 | 58 | R | 3 | 10 | 37 | 3 | 54 | 3 | St; Rop; Ras |
LevR, Carbidopa/levodopa sustained release; Lev, Carbidopa/levodopa (regular formulation); Pr, Pramipexole; Sel, Selegiline; Ent, Entacapone; Br, Bromocriptine; Rop, Ropinirole; St, Stalevo (Carbidopa/levodopa/entacapone); Ras, Rasagiline; Am, Amantadine; Rot, Rotigotine; Art, Artane (trihexyphenidyl) and Par, Parcopa.
a
Duration is years since the first remembered parkinsonian symptom.
b
UPDRS: United Parkinson’s Disease Rating Scale, Motor section (maximum score of 108). Higher scores indicate greater motor impairments.
c
H & Y stage: Hoehn and Yahr stage (maximum score of 5). Higher stages indicate more severe disease.
d
Tested off medications.