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. Author manuscript; available in PMC: 2014 Jan 17.
Published in final edited form as: Cell Host Microbe. 2013 Jul 17;14(1):104–115. doi: 10.1016/j.chom.2013.06.005

Figure 5. Adapting the format to drug screening.

Figure 5

(A) Inter-experimental variability measured by the coefficient of variation (CV) and infection rate using fresh and cryopreserved sporozoites from three different batches. (B) Inter-experimental variability measured by the coefficient of variation (CV) and infection rate using cryopreserved sporozoites from the same batch. (C) Heat map indicating levels of infection (green, highest EEF numbers; red, lowest EEF numbers) observed in 7 representative control or primaquine treated wells. Comparison yields positive Z factor. (D) P. falciparum infection with primaquine or atovaquone in 2 independent experiments performed on different days. (E) P. falciparum infection in MPCCs following two doses of fresh sporozoites determined by manual counts (M) or by image analysis automation (A). See also Figure S3. Error bars represent standard error of the mean (SEM). See also Figure S3.