Table 1.

Factors associated with early placement of CVC (CVC) in patients with septic shock.

Variable	Multivariable-adjusted predictors Early CVC vs. No CVC Odds Ratio (95% CI)
Age, per 1 year	0.99 (0.99-0.99)
Sex, female	1.12 (1.08-1.16)
Race/ethnicity
White	Ref
Black	1.08 (1.02-1.15)
Hispanic	0.78 (0.73-0.83)
Other/Unspecified	0.61 (0.58-0.64)
Per Comorbidity	1.11 (1.08-1.14)
Paralysis	1.36 (1.24-1.50)
Dementia	0.79 (0.74-0.84)
Chronic liver disease	0.90 (0.83-0.98)
Chronic kidney disease	0.89 (0.84-0.94)
COPD	0.95 (0.90-0.99)
Metastatic or hematologic malignanc	y 0.74 (0.70-0.79)
Per acute organ failure	1.31 (1.28-1.34)
Hematologic failure	0.94 (0.90-0.99)
Neurologic failure	0.84 (0.80-0.90)
Hepatic failure	0.86 (0.80-0.93)
Electrolyte abnormality	1.10 (1.06-1.14)
Critical care interventions
Arterial catheter	3.45 (3.23-3.66)
Mechanical ventilation	1.73 (1.66-1.81)
Dialysis	0.76 (0.71-0.81)
Right heart catheterization	0.69 (0.61-0.78)
Source of infection
Respiratory	1.08 (1.05-1.12)
Abdominal	1.11 (1.05-1.17)
Skin or soft tissue	1.19 (1.11-1.27)
Pathogen type
Gram positive	REF
Gram negative	0.87 (0.82-0.92)
None reported	0.86 (0.82-0.90)
US Geographic Region
Northeast	REF
Midwest	0.68 (0.64-0.73)
South	1.00 (0.95-1.05)
West	1.17 (1.12-1.22)
Hospital Bed size
Small	REF
Medium	1.03 (0.97-1.09)
Large	1.09 (1.03-1.16)
Hospital Location - Urban	1.26 (1.18-1.35)
Teaching Hospital	1.06 (1.02-1.10)
Payer
Medicare	REF
Medicaid	0.96 (0.90-1.02)
Private insurance	0.90 (0.85-0.94)
Self-pay	0.98 (0.88-1.09)
Other/No charge	1.05 (0.93-1.18)
Per Year	1.15 (1.14-1.15)

‘Early’ CVC was placed on the day of admission, c-statistic 0.742