Table 3.

Results from multivariate logistic regression analysis of respiratory symptoms and arsenic exposure in utero (10-499 µg/l and 500+ µg/l compared with never exposed)

	Age- and gender-adjusted				More variables adjusteda
Respiratory symptoms	10-499 µg/l OR (95% CI)	P-valueb	500+ µg/l OR (95% CI)	P-valueb	10-499 µg/l OR (95% CI)	P-valueb	500+ µg/l OR (95% CI)	P-valueb
Coughing
When having a cold (last 12 months)	1.71 (0.87–3.35)	0.06	1.87 (0.80–4.37)	007	1.81 (0.88–3.72)	0.05	1.76 (0.73–4.27)	0.10
When not having a cold (last 12 months)	1.80 (0.88–3.70)	0.05	2.53 (1.12–5.69)	0.01	1.58 (0.75–3.35)	0.12	2.23 (0.96–5.16)	0.03
Dry cough (last 12 months)	1.09 (0.71–1.69)	0.35	0.87 (0.51–1.48)	0.70	1.03 (0.65–1.64)	0.44	0.77 (0.44–1.34)	0.82
Wheezing
Ever	2.14 (1.36–3.36)	<0.001	2.17 (1.26–3.75)	<0.01	2.20 (1.37–3.55)	<0.001	2.13 (1.21–3.73)	<0.01
Last 12 months	1.31 (0.69–2.47)	0.20	1.46 (0.68–3.12)	0.17	1.20 (0.61–2.35)	0.30	1.23 (0.56–2.69)	0.31
Number of wheezing attacks (1- 3 times vs none)	0.90 (0.43–1.89)	0.61	1.18 (0.50–2.78)	0.35	0.83 (0.38–1.80)	0.68	1.03 (0.43–2.48)	0.47
Number of wheezing attacks (4+ times vs none)	3.12 (0.97–10.0)	0.03	2.80 (0.72–11.0)	0.07	3.29 (0.94–11.5)	0.03	2.60 (0.62–10.8)	0.10
Number of nights sleep being disturbed (<1 per week vs none)	1.20 (0.57–2.50)	0.31	1.80 (0.80–4.06)	0.08	1.13 (0.52–2.45)	0.38	1.55 (0.67–3.59)	0.15
Number of nights sleep being disturbed (1+ per week vs none)	1.39 (0.44–4.40)	0.29	0.74 (0.14–3.92)	0.64	1.50 (0.44–5.15)	0.26	0.71 (0.13–3.89)	0.65
Severe enough to affect speech	1.84 (0.90–3.75)	0.05	2.12 (0.92–4.88)	0.04	1.68 (0.79–3.57)	0.09	1.80 (0.76–4.26)	0.09
When after exercising	1.58 (0.72–3.47)	0.13	1.91 (0.76–4.79)	0.08	1.36 (0.60–3.10)	0.23	1.53 (0.59–3.95)	0.19
When not exercising	1.52 (0.48–4.75)	0.24	0.32 (0.04–2.83)	0.85	1.59 (0.48–5.25)	0.22	0.30 (0.03–2.80)	0.85
When having a cold	1.39 (0.73–2.65)	0.16	1.68 (0.79–3.57)	0.09	1.31 (0.67–2.59)	0.22	1.47 (0.67–3.21)	0.17
When not having a cold	4.32 (0.91–20.5)	0.03	8.41 (1.66–42.6)	<0.01	5.19 (1.04–25.9)	0.02	9.26 (1.71–50.1)	<0.01
Shortness of breath
Woken up with shortness of breath	1.57 (0.99–2.49)	0.03	1.56 (0.90–2.72)	0.06	1.60 (0.99–2.59)	0.03	1.54 (0.87–2.73)	0.07
Woken up with tightness of chest	1.35 (0.67–2.70)	0.20	1.81 (0.83–3.96)	0.07	1.22 (0.59–2.50)	0.29	1.65 (0.74–3.67)	0.11
When walking fast or climbing	2.74 (1.18–6.37)	<0.01	3.19 (1.22–8.32)	<0.01	2.53 (1.05–6.09)	0.02	2.70 (1.01–7.20)	0.02
When walking on level ground	2.30 (0.70–7.58)	0.09	3.86 (1.09–13.7)	0.02	2.46 (0.70–8.67)	0.08	3.46 (0.94–12.7)	0.03
Stops for breath when walking at own pace on level ground	1.91 (0.63–5.76)	0.13	1.34 (0.33–5.40)	0.34	2.28 (0.69–7.57)	0.09	1.21 (0.27–5.31)	0.40
Asthma	1.84 (1.04–3.26)	0.02	2.33 (1.19–4.57)	<0.01	1.80 (0.99–3.28)	0.03	2.21 (1.11–4.38)	0.01
Pneumonia	2.11 (1.30–3.43)	<0.01	1.43 (0.79–2.61)	0.12	2.20 (1.32–3.66)	<0.01	1.43 (0.78–2.65)	0.13

^aAdjusted for age, gender, mother’s education, father’s education, father’s smoking status and rooms in the house.

^bOne-sided.