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. Author manuscript; available in PMC: 2013 Sep 23.
Published in final edited form as: Annu Rev Immunol. 2012 Jan 3;30:357–392. doi: 10.1146/annurev-immunol-020711-075018

Figure 4.

Figure 4

Siglecs that lack defined cytoplasmic tail signaling motifs or a charged transmembrane residue. The cytoplasmic tail of Siglec-4 has a tyrosine residue (Y) that does not fit into any known consensus for signaling. It has been referred to in the literature as a Fyn phosphorylation site.