. 2013 Sep 23;8(9):e75210. doi: 10.1371/journal.pone.0075210

Table 1. Dead end metabolites from the EcoCyc database.

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (AI-2)^p	allantoin ^p	maltopentaose
(E)-3-(methoxycarbonyl)pent-2-enedioate	aminoacetaldehyde ^p	methanol ^p
(R)-beta-lysine	aminomethylphosphonate	methyl red
(R)-malate	an unknown C3 fragment	methyl-1,4-benzoquinol
(R)-pantolactone	benzaldehyde	methyl-1,4-benzoquinone
1-chloro-2,4-dinitrobenzene (CDNB)	CDP-choline	N,N'-dimethyl-p-phenylenediamine
1-deoxy-D-xylulose	cholate	N-alpha-acetyl lysine methyl ester
2,3-diaminopropionate	cis-vaccenate ^p	N-ethylmaleimide
2,4-dinitrophenyl-S-glutathione	CO	N-ethylsuccinimide
2-aminobutyrate	cobinamide ^p	nicotinamide riboside
2-aminomalonate-semialdehyde	cofactor	nigerose
2-dehydropantolactone	corresponding carbamoyl amino acid	N-methyltryptophan
2-deoxy-D-glucose	Cr3+	NMNH
2-deoxy-D-glucose 6-phosphate	Cr6+	octanoate ^p
2-deoxygluconate	curcumin ^p	oxalate
2-protocatechuoylphloroglucinolcarboxylate	D-4-hydroxy-2-keto-glutarate (KHG)	oxamate ^p
3,4-dihydroxyphenylacetate	d-biotin d-sulfoxide	phenylethylamine ^p
3,4-dihydroxyphenylacetyl-CoA	D-galactono-1,4-lactone	phenylhydantoin
3,5-tetradecadienoate^p	diacetyl	pre-cofactor
3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate	diacylglycerol pyrophosphate	pseudouridine ^p
3-chloro-D-alanine	dihydrolipoamide	psicoselysine ^p
3-dehydro-2-deoxy-D-gluconate	ethanolamine ^p	pyrazinamide
3-hydroxy-5-cis-tetradecenoyl-CoA^p	ethyl-(2R)-methyl-(3S)-hydroxybutanoate	pyrazinoate
3-hydroxypropionate^p	ethyl-2-methylacetoacetate	queuine
3-hydroxy-trans-cinnamate^p	fructoselysine ^p	quinate
3-mercaptopyruvate	GDP-alpha-D-glucose	S2- ^p
3-methylcrotonyl-CoA	glycerol 2-phosphate	S-adenosyl-4-methylthio-2-oxobutanoate ^p
3-phenylpropanoate^p	GMP-lysine	salicyl alcohol
3-sulfinoalanine (AKA cysteine sulfinic acid)	heptosyl-KDO2-lipid IVA	S-carboxymethyl-D-cysteine
4-(2-aminophenyl)-2,4-dioxobutanoate	hydroxylamine	selenate1,3-propanediol
4-coumarate	hydroxymethylpyrimidine (HMP)^p	selenite
4-coumaroyl-CoA	hydroxypropionaldehyde	S-methyl-5-thio-D-ribose ^p
4-methyl-5-(beta-hydroxyethyl)thiazole (THZ)^p	isovaleryl-CoA	S-methyl-L-methionine
4-nitrobenzaldehyde	kynurenine	tetrahydrocurcumin ^p
4-nitrobenzyl alcohol	L-glyceraldehyde 3-phosphate	tetrahydromonapterin ^p
5', 5'-diadenosine triphosphate	L-idarate	thioglycolate
5,6,7,8-tetrahydropteridine	linear dimeric GMP	trans-aconitate
5,6-dimethylbenzimidazole (DMB)^p	lipoamide	trans-cinnamate ^p
6,7-dihydropteridine	lipoate ^p	UDP-[N-acetyl-D-glucosamine]n
acetoacetate ^p	L-methionine sulfoxide	urate ^p
acetylmaltose	L-rhamnonate	urea ^p
adenosine thiamine triphosphate	L-selenocysteine
adenosylcobalamin-5'-phosphate	L-threo-3-phenylserine

^p DEMs derived from within EcoCyc metabolic pathways.