Table 2. Family data, regressive onset, cognitive and language development.
| Total sample | Experimental Groups | ||||||
| ASD-seizures | ASD-EEG | ASD “simplex” | Effect size | Test | p | ||
| Family History Epilepsy | |||||||
| Yes | 41 (20.4%) | 18 (43.9%) | 9 (22%) | 14 (34.1%) | Φc = 0.207 | χ2 = 8.582 | 0.014 |
| No | 160 (79.6%) | 37 (23.1%) | 67 (41.9%) | 56 (35%) | |||
| Family History Febrile Seizures | |||||||
| Yes | 21 (10.4%) | 11 (52.4%) | 5 (23.8%) | 5 (23.8%) | Φc = 0.192 | χ2 = 7.397 | 0.025 |
| No | 180 (89.6%) | 44 (24.4%) | 71 (39.4%) | 65 (36.1%) | |||
| Regressive onset | |||||||
| Yes | 82 (41.4%) | 27 (32.9%) | 34 (41.5%) | 21 (25.6%) | Φc = 0.173 | χ2 = 5.896 | 0.052 |
| No | 116 (58.6%) | 28 (24.1%) | 39 (33.6%) | 49 (42.2%) | |||
| Level of Cognitive Development * | |||||||
| Normal to Borderline | 84 (44.2%) | 15 (17.9%) | 32 (38.1%) | 37 (44%) | Φc = 0.187 | χ2 = 13.347 | 0.010 * |
| Mild to Moderate Delay | 68 (35.8%) | 21 (30.9%) | 22 (32.4%) | 25 (36.8%) | |||
| Severe Delay | 38 (20%) | 18 (47.4%) | 13 (34.2%) | 7 (18.4%) | |||
| Level of Language Development | |||||||
| Normal | 42 (20.4%) | 13 (31%) | 17 (40.5%) | 12 (28.5%) | Φc = 0.072 | χ2 = 2.121 | 0.714 |
| Delayed | 107 (51.9%) | 27 (25.2%) | 38 (35.5%) | 42 (39.3%) | |||
| Absent | 57 (27.7%) | 18 (31.6%) | 21 (36.8%) | 18 (31.6%) | |||
*
Severe cognitive delay is associated with the ASD-seizures group (see Figure 1, and CA in Table S4 in Supporting Information S1).
Φc = Cramers’ phi coefficient, χ2 = the Pearson chi-squared test.