Figure 4. Effect of minocycline treatment on striatal cytokine concentration in Wt and gp91^phox-/- 6-OHDA-lesioned mice.

Striatal concentration of pro-inflammatory (IL-1β, TNF-α, IFN-γ, IL-2) and anti-inflammatory cytokines (IL-10 and TGF-β1) and the chemokine RANTES following 6-OHDA-induced PD in Wt and gp91^phox-/- treated with minocycline or PBS. All concentrations were expressed in pg/ml. The statistical significance is expressed as: * P<0.05; ** P<0.01 and *** P<0.001; n=6 for each experimental group tested.