Table 1. Unique features of CoCiter compared with those of existing gene function analysis tools.
Category | Name | Input | Species | Type | Gene function enrichment analysis | Compare to user defined gene sets | Compare to user defined term sets |
GO-based | GOFFA | Genes | 3 | ArrayTrack plug-in | √ | ||
BinGO | Genes | 24 | Cytoscape plug-in | √ | |||
ClueGO | Genes | 14 | Cytoscape plug-in | √ | |||
ProfCom | Genes | 6 | Web + API | √ | |||
DAVID | Genes | Many | Web + API | √ | |||
FatiGO+ | Genes | 10 | Web | √ | √ | ||
Text mining -based | iHOP | Genes | 8 | Web | |||
Caipirini | Genes and terms | Many | Web + API | ||||
MEDIE | Genes and terms | Many | Web | ||||
Info-pubmed | Genes | Many | Web | ||||
GeneWizard | Genes and terms | Many | Standalone | √1 | |||
CoPub | Genes and terms | 3 | Web + API | √1 | |||
Marmite | Genes | Many | Web | √2 | √ | ||
Martini | Genes and terms | Many | Web + API | √3 | √3 | √3 | |
CoCiter | Genes and terms | Many | Web + API | √ | √ | √ |
by utilizing GO enrichment analysis.
limited to a small set of predefined terms.
only finds the differences between two conditions (conditions could be genes or terms) based on key words.