Skip to main content
. 2013 Sep 23;8(9):e74442. doi: 10.1371/journal.pone.0074442

Table 4. HLA Conserved Extended Haplotypes in 234 Mexican admixed individuals (468 haplotypes).

C-B-DRB1-DQB1 haplotype n H.F. Δ′ t C-B-DRB1-DQB1 haplotype n H.F. Δ′ t
Amerindian C*07∶02 B*39∶05 DRB1*04∶07 DQB1*03∶02 19 0.0406 0.5025 4.15 African C*06∶02 B*58∶02 DRB1*13∶01 DQB1*03∶03 4 0.0086 1.0000 2.02
C*07∶02 B*39∶06 DRB1*14∶06 DQB1*03∶01 16 0.0342 0.5482 3.89 Total 4 0.0086
C*04∶01 B*35∶17 DRB1*08∶02 DQB1*04∶02 14 0.0299 0.7256 3.64 Asian C*08∶01 B*15∶02 DRB1*12∶02 DQB1*03∶01 2 0.0043 1.0000 1.42
C*01∶02 B*15∶15 DRB1*08∶02 DQB1*04∶02 8 0.0171 0.5251 2.45 Total 2 0.0043
C*08∶01 B*48∶01 DRB1*08∶02 DQB1*04∶02 8 0.0171 1.0000 2.23 Unknown C*07∶02 B*39∶05 DRB1*08∶02 DQB1*04∶02 5 0.0107 −0.2267 −0.14
C*04∶01 B*35∶12 DRB1*08∶02 DQB1*04∶02 7 0.0150 0.3054 1.78 C*04∶01 B*53∶01 DRB1*13∶02 DQB1*06∶04 4 0.0086 0.6601 2.01
C*01∶02 B*15∶30 DRB1*08∶02 DQB1*04∶02 4 0.0086 0.3826 1.49 C*04∶01 B*35∶14 DRB1*16∶02 DQB1*03∶01 4 0.0086 0.6438 1.95
C*03∶05 B*40∶02 DRB1*04∶07 DQB1*03∶02 4 0.0086 0.3234 1.61 C*01∶02 B*35∶43 DRB1*04∶03 DQB1*03∶02 4 0.0086 0.4323 1.98
C*15∶02 B*51∶01 DRB1*08∶02 DQB1*04∶02 4 0.0086 0.3140 1.36 C*03∶04 B*40∶02 DRB1*16∶02 DQB1*03∶01 4 0.0086 0.3200 1.78
C*03∶05 B*35∶01 DRB1*04∶07 DQB1*03∶02 3 0.0064 0.5489 1.59 C*07∶02 B*39∶06 DRB1*04∶07 DQB1*03∶02 4 0.0086 0.0394 −0.66
C*04∶01 B*35∶17 DRB1*16∶02 DQB1*03∶01 3 0.0064 0.1096 1.14 C*01∶02 B*15∶01 DRB1*08∶02 DQB1*04∶02 3 0.0064 0.2944 1.13
C*07∶02 B*39∶05 DRB1*16∶02 DQB1*03∶01 3 0.0064 0.0295 0.49 C*04∶01 B*35∶01 DRB1*08∶02 DQB1*04∶02 3 0.0064 0.0121 0.09
C*03∶05 B*40∶02 DRB1*04∶04 DQB1*03∶02 3 0.0064 0.2538 1.48 C*07∶02 B*39∶05 DRB1*14∶02 DQB1*03∶01 3 0.0064 0.2158 1.37
C*03∶03 B*52∶01 DRB1*14∶06 DQB1*03∶01 3 0.0064 0.4455 1.55 C*08∶01 B*48∶01 DRB1*04∶04 DQB1*03∶02 3 0.0064 0.1472 1.28
C*01∶02 B*15∶01 DRB1*16∶02 DQB1*03∶01 2 0.0043 0.2368 1.17 C*15∶09 B*51∶01 DRB1*04∶07 DQB1*03∶02 3 0.0064 0.2482 1.27
C*01∶02 B*15∶30 DRB1*14∶06 DQB1*03∶01 2 0.0043 0.1682 0.93 C*07∶02 B*07∶02 DRB1*11∶04 DQB1*03∶01 2 0.0043 0.2235 1.28
C*04∶01 B*35∶24 DRB1*16∶02 DQB1*03∶01 2 0.0043 0.4658 1.32 C*01∶02 B*15∶01 DRB1*04∶04 DQB1*03∶02 2 0.0043 0.2385 1.18
C*01∶02 B*35∶43 DRB1*08∶02 DQB1*04∶02 2 0.0043 0.0396 0.21 C*04∶07 B*15∶31 DRB1*14∶01 DQB1*05∶03 2 0.0043 1.0000 1.42
C*07∶02 B*39∶01 DRB1*08∶02 DQB1*04∶02 2 0.0043 0.3826 1.05 C*05∶01 B*18∶01 DRB1*11∶01 DQB1*03∶19 2 0.0043 0.4946 1.41
C*03∶04 B*39∶02 DRB1*04∶11 DQB1*03∶02 2 0.0043 0.3896 1.39 C*04∶01 B*35∶01 DRB1*16∶02 DQB1*03∶01 2 0.0043 0.0740 0.77
C*07∶02 B*39∶02 DRB1*08∶02 DQB1*04∶02 2 0.0043 0.3826 1.05 C*06∶02 B*35∶02 DRB1*11∶04 DQB1*03∶01 2 0.0043 1.0000 1.42
C*03∶04 B*40∶02 DRB1*08∶02 DQB1*04∶02 2 0.0043 −0.0439 −0.06 C*04∶01 B*35∶12 DRB1*04∶04 DQB1*03∶02 2 0.0043 0.0672 0.75
C*08∶03 B*48∶01 DRB1*08∶02 DQB1*04∶02 2 0.0043 0.5884 1.25 C*04∶01 B*35∶12 DRB1*04∶07 DQB1*03∶02 2 0.0043 0.0133 0.14
Total 117 0.2504 C*04∶01 B*35∶12 DRB1*14∶06 DQB1*03∶01 2 0.0043 0.0296 0.31
C*01∶02 B*35∶43 DRB1*04∶04 DQB1*03∶02 2 0.0043 0.1708 1.09
Caucasian C*07∶02 B*07∶02 DRB1*15∶01 DQB1*06∶02 7 0.0150 0.4478 2.62 C*06∶02 B*37∶01 DRB1*01∶03 DQB1*05∶01 2 0.0043 0.6645 1.42
C*16∶01 B*44∶03 DRB1*07∶01 DQB1*02∶02 6 0.0128 0.7341 2.44 C*03∶04 B*39∶02 DRB1*04∶04 DQB1*03∶02 2 0.0043 0.3604 1.28
C*08∶02 B*14∶02 DRB1*01∶02 DQB1*05∶01 5 0.0107 0.4414 2.22 C*07∶02 B*39∶02 DRB1*16∶02 DQB1*03∶01 2 0.0043 0.4658 1.32
C*06∶02 B*13∶02 DRB1*07∶01 DQB1*02∶02 4 0.0086 0.7873 1.99 C*07∶02 B*39∶05 DRB1*14∶06 DQB1*03∶01 2 0.0043 −0.4015 −0.85
C*05∶01 B*18∶01 DRB1*03∶01 DQB1*02∶01 3 0.0064 0.5868 1.71 C*07∶02 B*39∶06 DRB1*04∶04 DQB1*03∶02 2 0.0043 0.0129 0.24
C*07∶01 B*57∶01 DRB1*07∶01 DQB1*03∶03 3 0.0064 1.0000 1.74 C*07∶02 B*39∶08 DRB1*04∶07 DQB1*03∶02 2 0.0043 0.6241 1.33
C*07∶01 B*08∶01 DRB1*03∶01 DQB1*02∶01 2 0.0043 0.6556 1.40 C*12∶03 B*39∶10 DRB1*07∶01 DQB1*02∶02 2 0.0043 1.0000 1.42
C*12∶03 B*38∶01 DRB1*04∶02 DQB1*03∶02 2 0.0043 0.3188 1.37 C*03∶04 B*40∶02 DRB1*04∶03 DQB1*03∶02 2 0.0043 0.1807 1.30
C*12∶03 B*38∶01 DRB1*07∶01 DQB1*02∶02 2 0.0043 0.2909 1.24 C*03∶04 B*40∶02 DRB1*14∶06 DQB1*03∶01 2 0.0043 0.0926 0.69
C*05∶01 B*44∶02 DRB1*04∶02 DQB1*03∶02 2 0.0043 0.4891 1.40 C*03∶05 B*40∶02 DRB1*14∶02 DQB1*03∶01 2 0.0043 0.1807 1.30
Total 36 0.0771 C*07∶01 B*41∶01 DRB1*08∶04 DQB1*03∶01 2 0.0043 1.0000 1.42
C*06∶02 B*45∶01 DRB1*07∶01 DQB1*02∶02 2 0.0043 1.0000 1.42
Caucasian shared with other populations C*08∶02 B*14∶01 DRB1*07∶01 QDB1*02∶02 3 0.0064 0.7341 1.71 C*07∶02 B*51∶01 DRB1*15∶01 DQB1*06∶02 2 0.0043 1.0000 1.42
C*07∶01 B*49∶01 DRB1*13∶02 DQB1*06∶04 3 0.0064 0.4902 1.72 C*15∶09 B*51∶01 DRB1*04∶11 DQB1*03∶02 2 0.0043 0.2353 1.35
C*04∶01 B*35∶01 DRB1*04∶04 DQB1*03∶02 3 0.0064 0.1472 1.28 C*15∶09 B*51∶01 DRB1*08∶02 DQB1*04∶02 2 0.0043 0.0396 0.21
C*08∶02 B*14∶02 DRB1*03∶01 DQB1*02∶01 2 0.0043 0.1547 1.22 C*03∶03 B*52∶01 DRB1*08∶02 DQB1*04∶02 2 0.0043 0.1768 0.69
C*04∶01 B*35∶01 DRB1*11∶04 DQB1*03∶01 2 0.0043 0.2252 1.29 Total 92 0.1975
C*04∶01 B*35∶01 DRB1*14∶01 DQB1*05∶03 2 0.0043 0.2252 1.29
C*07∶02 B*07∶02 DRB1*15∶02 DQB1*06∶01 2 0.0043 0.3788 1.35
C*06∶02 B*50∶01 DRB1*03∶01 DQB1*02∶01 2 0.0043 0.4834 1.38
Total 19 0.0407