Table 6. Measures of genetic diversity at the allele level for HLA system in a Mexican admixed population.
HLA Allele | O.H. | E.H. | p value | PIC | PD |
HLA-A | 0.8718 | 0.8919 | 0.5303 | 0.8776 | 0.7382 |
HLA-B | 0.9487 | 0.9668 | 0.2942 | 0.9544 | 0.8531 |
HLA-C | 0.9009 | 0.8947 | 0.2001 | 0.8845 | 0.7972 |
HLA-DRB1 | 0.9013 | 0.9193 | 0.0061 | 0.9123 | 0.7981 |
HLA-DQB1 | 0.8205 | 0.8256 | 0.2682 | 0.8020 | 0.6376 |
O.H.: Observed heterozygosity. E.H.: Expected Heterozygosity. p values <0.05 are considered statistically significative and thus reflect differences between O.H. and E.H. PIC: Polymorphism Information Contents. PD: Power of Discrimination.