Table 1. Demographic, clinical, and biochemical data.
| Variables | Controls | Kidney stones |
All | p (Control vs. All) | |
|---|---|---|---|---|---|
| COS | NCOS | ||||
| N | 84 | 74 | 39 | 113 | - |
| Mean±SD(range) age(yrs) | 56.9±4.56 (49-68) | 57.1±5.0 (48-67) | 57.9±4.96 (49-69) | 57.4±4.98 (48-69) | 0.491 |
| Mean±SD(range) AAM(yrs) | 49.9±1.28 (46-52) | 49.3±1.04 (47-52)* | 49.7±0.89 (48-51)# | 49.4±1.01 (47-52) | 0.001 |
| Mean±SD(range)TSM (yrs) | 6.9±4.78 (1-17) | 7.8±5.12 (1-18) | 8.2±5.02 (1-19) | 8±5.08 (1-19) | 0.132 |
| Mean±SD(range)BMI(kg/m2) | 24.5±3.16 (15.8-32.5) | 22.4±2.45 (17.6-28.7)* | 24.9±3.33 (17.3-31.2)# | 23.2±3.01 (17.3-31.2) | 0.004 |
| WDC(<2L/d) | 27 (32.1%) | 34 (45.9%) | 18 (46.2%) | 52 (46%) | 0.049 |
| WET(>28°C) | 13 (15.5%) | 20 (27%) | 11 (28.2%) | 31 (27.4%) | 0.046 |
| HTN (%) | 29 (34.5%) | 30 (40.5%) | 17 (43.6%) | 47 (41.6%) | 0.313 |
| DM (%) | 12 (14.3%) | 14 (18.9%) | 7 (17.9%) | 21 (18.6%) | 0.424 |
| RA | 31 (36.9%) | 42 (56.8%)* | 19 (48.7%) | 61 (54%) | 0.018 |
| Mean±SD (range) T (ng/ml) | 0.26±0.14 (0.01-0.68) | 0.26±0.17 (0.01-0.84) | 0.28±0.22 (0.01-0.94) | 0.27±0.19 (0.01-0.79) | 0.786 |
| Mean±SD (range) E2 (pg/mL) | 31.1±16.64 (2-94) | 18.3±11.94 (2-78)* | 26.5±14.88 (2-60)# | 21.1±13.54 (2-78) | <0.001 |
SD, standard deviation; COS, calcium oxalate stones; NCOS, non-calcium oxalate stones; AAM, age at menopause; TSM, time since menopause ; BMI, body mass index; WDC, water drink consumption; WET, working environment temperature; HTN, hypertension; DM, diabetes mellitus; RA, rural area of life; T, testosterone; E2, estradiol. P-values were determined using the Wilcoxon rank sum test, or the chi-square tests between all patients and controls subjects. Post-hoc analyses were performed for comparison of variables between the following cohorts: COS, NCOS, controls, COS versus NCOS, COS versus controls, and NCOS versus controls, with p-values<0.05 considered significant."* "indicate group is significantly from the control."#" indicate group is significantly from the COS.