Figure 7. Memory is only modestly affected by age.

A significant effect of age on the performance of the probe test was observed, with 1.5-month old mice spending significantly more time in the target quadrant (A) and crossing the platform zone more often (B) than their oldest counterparts. (C) Representative examples of swim paths of 1.5- and 12-month old mice during the probe test. Although both mice swam in the quadrant where the platform used to be located, the younger animal swam predominately more in the target quadrant. Data are presented as means ± SEM. * p < 0.05, ** p < 0.01, see text for additional statistical details.