Table 1.
Comparisons of Performance Metrics Between the Dexcom G4 Platinum and SEVEN PLUS Systems
| Parameter | DG4P | DSP | P value |
|---|---|---|---|
| Sensors (n) | 108 | 67 | — |
| Number of samples paired with reference (YSI) | 13,538 | 1,827 | — |
| %20/20 mg/dL | 82% | 76% | <0.0001 |
| MAD (mg/dL) | 21 | 25 | <0.0001 |
| MARD | 13% | 16% | <0.0001 |
| Within biochemical hypoglycemia (YSI ≤70 mg/dL) | |||
| MAD (mg/dL) | 11 | 16 | <0.0001 |
| MARD | 18% | 27% | <0.0001 |
| Percentage of CGM values that were ≤70 mg/dL when severe hypoglycemia (YSI ≤55 mg/dL) | 88% | 73% | 0.015 |
| CEG Zone A | |||
| Day 1 | 70% | 73% | 0.0003 |
| Day 4 | 85% | 75% | <0.0001 |
| Day 7 | 83% | 68% | <0.0001 |
| Overall | 79% | 73% | <0.0001 |
| Aggregate MARD | |||
| Day 1 | 16.7% | 16.2% | 0.534 |
| Day 4 | 11.4% | 14.3% | <0.0001 |
| Day 7 | 11.9% | 17.7% | <0.0001 |
| CEG Zone A within biochemical hypoglycemia (YSI <70 mg/dL) | 70% | 53% | <0.0001 |
| Mean paired sensor coefficient of variation | 7% | 11% | <0.001 |
| Sensor daily display rate | 97% | 90% | <0.001 |
| Sensor duration (% of 7 days) | 94% | 89% | 0.278 |
CEG, Clarke error grid; CGM, continuous glucose monitoring; DG4P, Dexcom G4 Platinum; DSP, Dexcom SEVEN PLUS; MAD, mean absolute difference; MARD, mean absolute relative difference; YSI, reference value measured with the YSI blood glucose analyzer.