Table 4. Isotopic fractionation (ΔIF, in ‰) measured for key metabolic transitions between a precursor and its product in lean (ZDF, (fa/+)) and diabetic (ZDF (fa/fa)) rats.
| Precursor/product | ZDF (fa/+) rat | ZDF (fa/fa) rat | P value | |
|---|---|---|---|---|
| ΔIF,‰ | ΔIF,‰ | |||
| Glucose/C16:0 | 2.39 ± 0.38 | 2.01 ± 0.36 | 0.877 | |
| C16:0/C18:0 | -1.04 ± 0.4 | -0.76 ± 0.18 | 0.007 | |
| C18:0/C18:1 | - 0.04 ± 0.64# | -1.67 ± 0.28 | 0.103 | |
| C18:2/C20:4 | -1.31 ± 0.45 | - 0.006 ± 0.53# | 0.232 |
ΔIF, ‰ (δA - δB) where A/B is the precursor/product ratio. Based on the Wilcoxon Signed Rank Test, all the data were significantly different from zero except for those marked with “#”.