Table 1.
Study Variables by Cohort and hsCRP group.
| Categorical Variables: Frequencies (Percents) Continuous Variables: Mean (SD) or Geometric Mean [1st quartile, 3rd quartile] |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Low (hsCRP ≤ 1) | Middle (1 < hsCRP≤ 3) | High (hsCRP > 3) | |||||||
| Adult | Adolescent | p† | Adult | Adolescent | p† | Adult | Adolescent | p† | |
| Variable | (N = 159) | (N = 165) | (N = 160) | (N = 71) | (N = 165) | (N = 46) | |||
| hsCRP (mg/dl)‡ | 0.49 [0.30, 0.90] | 0.32 [0.20, 0.60] | <.001 | 1.74 [1.40, 2.20] | 1.79 [1.40, 2.30] | 0.680 | 5.17 [3.90, 6.50] | 5.19 [3.80, 6.90] | 0.934 |
| Age (yrs) | 37.08 (7.91) | 16.22 (1.75) | 38.16 (7.31) | 16.08 (1.61) | 37.94 (7.26) | 16.25 (1.58) | |||
| Gender Female | 55 (34.6%) | 69 (41.8%) | 0.282 | 76 (47.5%) | 38 (53.5%) | 0.563 | 111 (67.3%) | 29 (63.0%) | 0.680 |
| Smoking | 106 (66.7%) | 6 (3.7%) | <.001 | 95 (59.4%) | 3 (4.3%) | <.001 | 99 (60.0%) | 0 (0%) | <.001 |
| Alcohol Use | 83 (52.2%) | 8 (4.9%) | <.001 | 81 (50.6%) | 8 (11.6%) | <.001 | 68 (41.2%) | 1 (2.3%) | <.001 |
| Obesity | 43 (27.0%) | 51 (30.9%) | 0.561 | 86 (53.8%) | 53 (74.6%) | 0.007 | 114 (69.1%) | 41 (89.1%) | 0.014 |
| Hypertensive Meds | 47 (29.6%) | 58 (36.3%) | 64 (38.8%) | ||||||
| Blood Pressure Pre HTN | 37 (23.3%) | 34 (20.6%) | <.001 | 38 (23.8%) | 21 (29.6%) | <.001 | 42 (25.5%) | 14 (30.4%) | <.001 |
| HTN | 60 (37.7%) | 6 (3.6%) | 74 (46.3%) | 2 (2.8%) | 73 (44.2%) | 1 (2.2%) | |||
| Metabolic Syndrome | 18 (11.3%) | 7 (4.2%) | 0.037 | 42 (26.3%) | 17 (23.9%) | 0.787 | 66 (40.0%) | 15 (32.6%) | 0.499 |
| Glucose Tolerance: Impaired | 22 (13.8%) | 27 (16.5%) | 0.444 | 19 (11.9%) | 15 (21.1%) | 0.063 | 33 (20.0%) | 13 (28.3%) | 0.363 |
| Diabetic | 4 (2.5%) | 1 (0.6%) | 13 (8.1%) | 1 (1.4%) | 18 (10.9%) | 2 (4.3%) | |||
†
Fishers exact test (categorical) or Student's t-test (continuous); adjustments made for multiple testing
‡
Data natural log transformed: geometric means with [first quartile, third quartile] presented
Obesity: ≥95th percentile (adolescents), ≥30 BMI (adults)
Metabolic Syndrome: 3 or more of following: Waist circumference ≥ 102 cm (males), ≥88 (females); SBP ≥120/80 mmHg (adolescents), ≥130/85 or HTN Rx (adults); HDL <40 mg/dl (males) or <50 (females); Triglycerides ≥110 mg/dl (adolescents) ≥150 (adults); Fasting glucose ≥110 mg/dl
HTN: BP ≥ 140/90 mmHg or HTN Rx (adults), BP percentile ≥ 95 (adolescents)
PreHTN: BP ≥ 120/80 mmHg. To convert hsCRP to SI units multiply by 9.524