Fig. 6.

A 17-year-old man with solitary and plexiform neurofibromas, diagnostic of NF1. a Axial T2-weighted MR image at the level of the masticator space shows multiple nodules, some of which (white arrow in b) show the “target appearance”—hypointense centre and hyperintense peripheral rim—suggestive of neurofibroma. The largest one is superficial to the mandibular ramus and has a heterogeneous appearance (black dot). b Coronal fat-suppressed contrast-enhanced T1WI shows tortuous expansion of small nerves in the masticator space (white arrow in b), compatible with plexiform neurofibromas