Fig. 14.

Pregnancy-associated breast cancer: a 36-year-old woman, 19 weeks pregnant, presenting with a palpable lump. Mammogram (a, b) reveals a dense partially circumscribed mass in the upper outer quadrant with associated microcalcifications. c Grey-scale ultrasound shows a hypoechoic ill-defined mass with hyperechoic foci of microcalcifications. d Power Doppler shows internal vascularity. e Microscopic high-power image (40×) shows grade 3 invasive ductal carcinoma with lack of tubule formation, pleomorphic nuclei and abundant mitotic figures