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. 2013 Mar 9;70(20):3893–3905. doi: 10.1007/s00018-013-1302-8

Table 1.

Aurora-A-binding proteins associated with primary cilia kinetics

Protein name Cell cycle or stimuli Effects on Aurora-A Function Ref.
Calcium–calmodulin (Ca2+/CaM) Cell cycle re-entry Activationa Primary cilia disassembly [46, 96]
Calcium ionophores Primary cilia disassembly [46, 96]
Mitosis Some mitotic functions of Aurora-A [46, 96]
HEF1 Cell cycle re-entry Activationa Primary cilia disassembly [44]
Mitosis Some mitotic functions of Aurora-A [44, 52]
Pitchfork (Pifo) Cell cycle re-entry Activationa Primary cilia disassembly [45]
Mitosis? Some mitotic functions of Aurora-A? [45]
Trichoplein Cell proliferation (especially at G1 phase) Activationa Suppression of aberrant primary cilia formation [47]

aInduction of Aurora-A autophosphorylation at Thr288