Table 1.
Protein name | Cell cycle or stimuli | Effects on Aurora-A | Function | Ref. |
---|---|---|---|---|
Calcium–calmodulin (Ca2+/CaM) | Cell cycle re-entry | Activationa | Primary cilia disassembly | [46, 96] |
Calcium ionophores | Primary cilia disassembly | [46, 96] | ||
Mitosis | Some mitotic functions of Aurora-A | [46, 96] | ||
HEF1 | Cell cycle re-entry | Activationa | Primary cilia disassembly | [44] |
Mitosis | Some mitotic functions of Aurora-A | [44, 52] | ||
Pitchfork (Pifo) | Cell cycle re-entry | Activationa | Primary cilia disassembly | [45] |
Mitosis? | Some mitotic functions of Aurora-A? | [45] | ||
Trichoplein | Cell proliferation (especially at G1 phase) | Activationa | Suppression of aberrant primary cilia formation | [47] |
aInduction of Aurora-A autophosphorylation at Thr288